Mahmudova Iroda Oktam
By: Iroda Mahmudova
Abstract: This article discusses the main part of the complex of problems faced by women, namely, uterine fibroids. It is often passed without clear symptoms and can be suddenly detected. The emergence of uterine fibroids, its risks, and treatment options are highlighted. Ways to preserve reproductive function without hysterectomy are outlined.
Keywords: Uterine fibroids, submucosal fibroids, myomectomy, hysterectomy, laparoscopy, reproductive health.
Introduction: Uterine fibroids are well-defined, encapsulated, high-quality nodules that arise from the smooth muscle fibers of the uterine body and cervix. They occur in 20-50% of women of reproductive age, with the majority occurring in women aged 20-50. Uterine fibroids are classified based on their location into uterine body (95%) and cervix (5%).
Depending on the location within the uterine wall, they may be intramural within the myometrium, submucosal beneath the endometrial lining, or subserosal outside the uterine serosa. Submucosal fibroids are considered the most dangerous due to their proximity to the uterine cavity. Fibroids may be solitary or multiple, and their size varies, typically increasing with each menstrual cycle.
Main Part: Several factors may contribute to the development of uterine fibroids. Primarily, hormonal changes, namely an increase in the levels of estrogen and progesterone in the blood, are associated with the proliferation of mitotic activity.
The physiological regulators of myometrial cell proliferation are considered to be sex steroid hormones. In some women, the increased number of estrogen receptors in the myometrium may contribute to the development of uterine fibroids.
After menopause, the growth of fibroids is usually not observed as the hormonal levels decline. Other contributing factors include genetic predisposition, abortion, obesity, high blood pressure, stress, and early menstruation. Many the two main types of surgical interventions are myomectomy and hysterectomy.
Myomectomy involves the removal of the fibroids while preserving the uterus, which is crucial for maintaining reproductive function. There are various methods of myomectomy, such as laparotomy, laparoscopic, and hysteroscopic myomectomies, each with its benefits and considerations. Gynecologists typically recommend myomectomy as the first-line treatment for symptomatic fibroids, with hysterectomy being reserved for specific indications.
Conclusion: Uterine fibroids are prevalent and often asymptomatic in women, requiring careful monitoring and management. Asymptomatic fibroids can be observed with confidence and caution. The initial approach to treating symptomatic fibroids is often medical therapy, with surgical intervention reserved for appropriate indications. Hysterectomy is an effective treatment for eliminating fibroids but poses challenges to preserving reproductive function. Myomectomy, as a uterus-preserving option, is being increasingly utilized in contemporary practice. The choice between medical and surgical interventions depends on the severity of symptoms, the size and location of fibroids, and the woman’s future fertility desires.
Mahmudova Iroda Oktam is identified as a student at the 2nd stage of Tashkent Medical Academy.
The email address “imaxmudova327@gmail.com” is also provided.